Copper Peptide Serum

You can use vitamin C and hyaluronic acid in your routine, but we recommend applying them separately from your anti-aging peptides. Copper peptides and vitamin C can interact in ways that reduce the efficacy of both ingredients when combined in the same formulation.

For best results: Apply your signal peptides first on clean skin to support collagen synthesis and skin barrier function, wait 60 seconds for absorption, then layer hyaluronic acid or vitamin C products if desired. This separation preserves the effectiveness of each ingredient.

Research published in the International Journal of Molecular Sciences examines how GHK-Cu signal peptides interact with dermal fibroblasts to support collagen synthesis pathways and extracellular matrix processes. Studies suggest these carrier peptides may help improve the appearance of skin elasticity and skin firmness through tissue repair mechanisms with consistent use.

These anti-aging peptides work by supporting wound healing processes and skin regeneration at the cellular level, which contributes to visible improvements in skin barrier function and overall appearance.

Important note: As a cosmetic product, our formulation works on the appearance of skin. We describe visible improvements (firmer-looking skin, improved texture appearance) rather than making structure or function claims.

GHK-Cu is a copper tripeptide composed of three amino acids (glycine, histidine, lysine) bound to copper. As both a signal peptide and carrier peptide, research examines it for tissue repair, wound healing, and collagen synthesis pathways.

Matrixyl 3000 is a dual-peptide complex (Palmitoyl Tripeptide-1 and Palmitoyl Tetrapeptide-7) consisting of matrikine signal peptides studied for extracellular matrix communication and skin cell signaling. Clinical research shows improvements in the appearance of skin firmness and fine lines.

Our Face Tonic combines both anti-aging peptides at clinically studied concentrations for comprehensive support of skin appearance through complementary mechanisms.

Yes! Copper peptides are generally compatible with retinol and niacinamide. Apply your signal peptides first on clean skin to initiate collagen synthesis and skin barrier support, let them absorb for 60 seconds, then layer your retinol or niacinamide products.

If you're new to combining active ingredients, introduce one product at a time and monitor how your skin responds. Some people prefer using retinol at night and anti-aging peptides in the morning to simplify their routine while maintaining skin regeneration benefits.

The main difference is formulation philosophy. Many brands dilute signal peptides and carrier peptides with hyaluronic acid, amino acids, or other ingredients in the same bottle. While those ingredients aren't harmful, they reduce the concentration of what clinical research actually studied for wound healing and tissue repair.

PLU's Face Tonic delivers GHK-Cu and Matrixyl 3000 anti-aging peptides at clinically studied concentrations without dilution, maximizing collagen synthesis and skin barrier function. Our Hair Tonic does the same with GHK-Cu and Acetyl Tetrapeptide-3 for optimal hair health. If you want additional ingredients like hyaluronic acid, you can layer them separately after the peptides absorb.

Copper peptides are generally well-tolerated across skin types, including sensitive skin. Our formulations use clinically studied concentrations of signal peptides without unnecessary ingredients that could trigger irritation or compromise skin barrier function.

If you have very sensitive skin or concerns about new products, we recommend patch testing: Apply a small amount to your inner forearm, wait 24 hours, and monitor for any reaction before applying to your face or scalp.

Most customers notice initial improvements in skin texture and appearance within 2-4 weeks of consistent daily use as signal peptides begin supporting tissue repair and skin barrier function. More significant visible improvements in skin firmness, skin tone, crow's feet, and fine lines typically appear around the 6-8 week mark as collagen synthesis pathways become established.

For hair health and density improvements, research on copper peptides and Acetyl Tetrapeptide-3 suggests visible results within 8-12 weeks of consistent application to the scalp as wound healing and skin regeneration processes support follicle function.

Individual results vary based on age, skin type, and consistency of use. The key is daily application of these anti-aging peptides - both morning and night if possible - to maintain extracellular matrix support.

Research on GHK-Cu signal peptides examines their role in supporting processes related to skin appearance through collagen synthesis and extracellular matrix support. Clinical studies describe improvements in the appearance of skin tone evenness and visible reduction in crow's feet and fine lines with consistent carrier peptide application.

When we say anti-aging peptides "improve skin tone," we're describing visible appearance benefits - more even-looking complexion, reduced appearance of discoloration, and smoother texture supported by enhanced skin barrier function - not making claims about altering skin structure.

PLU serums contain both signal peptides and carrier peptides that work through complementary mechanisms. GHK-Cu functions as both - as a signal peptide, it communicates with cells to support wound healing and tissue repair; as a carrier peptide, it delivers copper ions to support collagen synthesis and skin regeneration processes.

Matrixyl 3000 contains matrikine signal peptides that support extracellular matrix communication, while Acetyl Tetrapeptide-3 works as a biomimetic signal peptide for hair health. Together, these anti-aging peptides create comprehensive support for skin barrier function and visible appearance improvements.

Absolutely! Many customers use both products as part of their daily routine. Face Tonic's signal peptides target skin firmness and texture appearance through collagen synthesis, while Hair Tonic's carrier peptides focus on scalp health and hair health through tissue repair mechanisms.

Apply Face Tonic to clean facial skin first to initiate skin barrier support, then apply Hair Tonic to your scalp. Both anti-aging peptides absorb in about 60 seconds, so you can complete your entire routine in under 2 minutes.